Want to know what Stanford’s most interesting neuroscientist is up to these days? Dr. Andrew Huberman has been diving deep into something that could change how we think about aging and energy – and I’ve been following his work closely.
Here’s the deal: Huberman’s been experimenting with these compounds called NMN and NR. If you’re scratching your head, don’t worry – they’re basically precursors to something called NAD+, which our cells need for energy. Think of NAD+ as your body’s battery pack, and these supplements as the chargers.
What gets me excited about Huberman’s approach is that he’s not selling some fantasy of living forever. Instead, he’s asking practical questions: Can we feel better? Think clearer? Perform better? As someone who geeks out over brain science, I love that he’s bringing his Stanford lab expertise to questions that actually matter for everyday life.
I’ve spent hours going through his research and protocols (yes, I’m that kind of nerd), and what’s fascinating is how he’s testing these supplements on himself while keeping the scientific rigor intact. It’s like watching a scientist turn himself into a living laboratory – but with the careful precision you’d expect from a Stanford professor.
Let’s dig into what he’s discovered about boosting NAD+ levels and why it matters for anyone interested in peak performance. Fair warning: what you’re about to read might change how you think about aging and energy – it certainly did for me.
Andrew Huberman’s NMN & NR Dosage & Brand
I’ve been digging into Huberman’s approach to NMN and NR dosing, and it’s pretty interesting how he didn’t just follow the standard recommendations. He actually took the time to experiment and find what worked best for him – you know, real trial and error stuff, backed by his scientific background.
Let me break down what I’ve learned about how he figured out his daily doses. It’s not just some random numbers he pulled out of thin air – this guy actually tracked how different amounts affected his energy, focus, and overall feeling throughout the day. Being the scientist he is, he kept detailed notes on everything (classic Huberman move, if you ask me).
- Renue by Science Liposomal NR – 500mg in capsule form
- Renue by Science Pure Powder NMN – 1-2 grams daily sublingually
Supplementation Synergy
When it comes to NMN & NR supplementation, Huberman has honed his regimen to precision. In a recent AMA on the Huberman Lab podcast, he revealed that he routinely ingests 500 milligrams of Nicotinamide Riboside (NR) in supplemental form. NR, known for its potential to bolster NAD+ levels, finds its place in Huberman’s daily routine. In a recent Tweet, Huberman claims he uses Renue by Science as his go-to brand for longevity supplements and says they don’t pay him a dime.
But that’s not where his journey ends. Dr. Huberman also incorporates Nicotinamide Mononucleotide (NMN) into his regimen—a sublingual powder by Renue by Science that dissolves swiftly beneath the tongue. You can get a 3-month supply of NMN powder from Renue by Science for just $67 using code ‘brainflow’ at checkout. The dosage ranges from 1 to 2 grams daily, each granule holding the promise of NAD+ enhancement.
RELATED READING: Andrew Huberman’s Complete Supplement List
A Calculated Cocktail of NMN & NR
What I really respect about Huberman’s work is how he approaches testing these supplements. He doesn’t just pop both pills and hope for the best. He actually takes the time to try NR and NMN separately, carefully noting how each one affects him. Sometimes he’ll use them together to see if they work better as a team. Pretty thorough, right?
But here’s what’s refreshing about his whole approach – he’s not out here claiming these supplements will help you live to 150. His goal is much more practical: he wants sustainable energy to power through his busy days. We’re talking about the kind of energy that helps you crush your work and workouts, but won’t leave you staring at the ceiling at 3 AM.
From following his work, it’s clear that Huberman isn’t caught up in the whole anti-aging hype that surrounds these supplements. While other researchers are debating whether NMN and NR might extend lifespan (spoiler: we still don’t know), Huberman keeps it real. He’s focused on something much simpler: feeling and performing better today. And honestly, that’s something I can get behind.
The Benefits of Increased NAD Levels
Aging is an inevitable journey that every living being embarks upon. As the years pass, our bodies undergo a myriad of changes, and a prominent player in this complex process is the decline of nicotinamide adenine dinucleotide (NAD+). NAD+, often hailed as the “currency of life,” is a crucial coenzyme that plays a pivotal role in countless cellular processes. This decline in NAD+ levels has been implicated in age-related ailments, making it a subject of immense interest for those seeking to age gracefully and maintain optimal health.
Enter Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR), two remarkable compounds that have garnered attention for their potential to counteract the effects of declining NAD+ levels as we age. These compounds, often referred to as NAD+ precursors, have been shown in human studies to bolster NAD+ levels in cells, offering a glimmer of hope in the quest to turn back the hands of time.
The benefits of supplementing with NMN and NR are multi-faceted. Firstly, these compounds hold the promise of bolstering cellular energy production. NAD+ serves as a critical component in the process of converting food into energy, and by replenishing NAD+ levels, NMN and NR may help rejuvenate cellular metabolism. This can translate into increased vitality and sustained energy levels, enabling individuals to maintain an active lifestyle and engage in activities they cherish.
Secondly, the role of NAD+ extends beyond energy production. It acts as a key player in DNA repair, protecting the genome from damage and ensuring the integrity of our genetic code. With age, the body’s ability to repair DNA diminishes, making it susceptible to mutations that can contribute to aging-related diseases. By elevating NAD+ levels, NMN and NR may aid in fortifying the body’s natural defenses against DNA damage, potentially reducing the risk of age-associated diseases.
Finally, NAD+ is intricately linked to the regulation of various cellular processes, including those related to inflammation and oxidative stress. Aging is often accompanied by chronic inflammation and increased oxidative stress, which can contribute to a range of age-related ailments, from cardiovascular issues to neurodegenerative diseases. NMN and NR, by replenishing NAD+, may help maintain a healthier balance in these processes, potentially mitigating the impact of aging on overall health and well-being.
While the scientific understanding of the full spectrum of benefits offered by NMN and NR is still evolving, these NAD+ precursors hold significant promise as tools for combating the effects of aging. As research continues to shed light on their mechanisms and effectiveness, individuals looking to optimize their health and vitality in their later years have compelling reasons to explore the potential benefits of NMN and NR supplementation.
Huberman’s NAD+ Injection Experience
Dr. Andrew Huberman’s relentless pursuit of vitality led him to explore the unconventional world of NAD+ injections. These injections offer a direct method of increasing NAD+ levels within the body by infusing NAD+ directly into the bloodstream, bypassing the digestive system.
However, Huberman’s personal account highlights the discomfort associated with NAD+ infusions. Many individuals experience nausea during the process, often requiring anti-nausea medication for relief. In Huberman’s case, he chose to forego additional medications, opting for minimal intervention.
Despite the initial discomfort, Huberman reports significant benefits from his NAD+ infusion experiences. These include improved sleep, increased vigor, and an overall sense of rejuvenation, particularly when recovering from illness. While his personal accounts are intriguing, it’s important to note that there are no formal clinical trials exploring NAD+ infusions for enhancing overall well-being at the time of Huberman’s statements.
Huberman’s willingness to venture into this uncharted territory underscores his dedication to self-experimentation and the pursuit of knowledge in the quest for vitality. His experiences serve as a reminder that the journey toward self-optimization often leads us down unexpected paths in the ever-evolving landscape of human health and wellness.